Clodronate (clodronate disodium, Bonefos®) is a non-nitrogen-containing bisphosphonate that inhibits osteoclast activity, and thereby inhibits bone resorption. • doses em termos de Clodronato dissódico. Estabilidade após diluição com Cloreto de Sódio 0,9% ou Glicose 5%. MedicinaNET - Todos os direitos reservados. Excipients Capsules. Bulk solution: phosphate buffered saline (20mM sodium phosphate, 09wt% NaCl), pH 7.0-7.5 LEGENDS: AL = Alveoli in lung. Advertising revenue supports our not-for-profit mission. Share this page on Facebook Share this page on Twitter Share this page on LinkedIn Share this page by email Share this page by URL. Tribo™ Human IFN gamma ELISA Kit; Tribo™ Human β2-microglobulin ELISA Kit; Human TNFꭤ ELISA kit; 1 step and 1hr; Fast Human TGF-β1 ELISA Drug information provided by: IBM Micromedex. Clodronate, Disodium Salt - CAS 22560-50-5 - Calbiochem 1 Product Result | Match Criteria: Product Name Sodium clodronate is used with other drugs to reduce the breakdown of bone caused by cancer that has spread to the bones. BM = Bone marrow. Site designed by Pharma Professional Services and developed by Hasan Computing Systems. hipercalcemia devido a tumores malignos ou metástases ósseas; osteólise (dissolução do osso) devido a metástase de tumores sólidos (câncer de mama, próstata ou tireoide) ou devido a neoplasia sanguínea (mieloma múltiplo). Severity of interaction: Moderate Evidence for interaction: Study. Clodronate sodium, also called clodronate disodium, is the disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. •interromper o tratamento se ocorrer comprometimento da função dos rins. medicamentos C. setTimeout("$('adwords').hide();", 10000); Generic name: clodronate. This content does not have an Arabic version. (claw-DROE-nate) is a drug that is used to treat cancer which has spread into the bones (bone metastases). O MedicinaNET é o maior portal médico em português. This medicine is available only with your doctor's prescription. Descriptions. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for SODIUM CLODRONATE. Clodronate works by reducing the breakdown of bone.This medication may be available under multiple brand names and/or in several different forms. Sodium clodronate (Bonefos, Clasteon, Loron) Sodium clodronate is a type of bisphosphonate. What is this drug used for? Dermatológico: hipersensibilidade na pele. Description and Brand Names. It is a capsule that you take by mouth. Share this page. Who? 12 Equine Key Opinions Leaders in English Performance, Western Performance, Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. It is also used to treat the increased amount of calcium in the blood (hypercalcemia) that may occur with some kinds of cancer. This content does not have an English version. Purified talc, calcium stearate, anhydrous colloidal silica, lactose, gelatin, purified water, iron oxide red, iron oxide yellow, Tekprint SW-9008 black ink and titanium dioxide. Osteolytic lesions, hypercalcaemia and bone pain associated with skeletal metastases in patients with breast cancer or multiple myeloma. Reúne recursos indispensáveis e conteúdos de ponta contextualizados à realidade brasileira, sendo a melhor ferramenta de consulta para tomada de decisões rápidas e eficazes. Many drugs have more than one name and, therefore, the same drug may be listed more than once. Both types of Clophsome ® are offered in the standard suspension form fo rthe convenience of use, the high potency form fo rdosing of high cotent with limited small volume and the lyophilized forms for the long shelf-life. dados não disponibilizados; não amamentar. For Adult. Clodronate DRUG NAME: Clodronate SYNONYM(S): Clodronate disodium, clodronic acid, Cl 2MDP, dichloromethylene bisphosphonate, disodium clodronate, sodium clodronate COMMON TRADE NAME(S): CLASTEON®, BONEFOS ; OSTAC CLASSIFICATION: Bone metabolism regulator. Parecoxib is predicted to increase the risk of renal impairment when given with clodronate. Generic names: clodronate disodium, clodronic acid disodium tetrahydrate; Brand names: Clasteon, Clastoban, Climaclod, Clodeosten, Clodran, Clodron, Clody, Difosfonal, Disdual, Lodronat, Loron, Lytos, Mebonat, Moticlod, Niklod, Ossiten, Ostac, Osteonorm, Osteostab, Sindronat; References ↑ Drug information provided by: IBM Micromedex. This multi-page article lists pharmaceutical drugs alphabetically by name. Previous Drug Generic - Next Drug Generic. setTimeout("$('adwordstopo').hide();", 10000); Injetável (solução) 1500 mg/25 mL: Bonefós. Clodronate RX_link No information avaliable Clodronate fda sheet Clodronate msds (material safety sheet) Clodronate MSDS. Sodium clodronate is a bisphosphonate and is prescribed for problems which affect bones. About Us. 1. CLODRONATO ABC Active Ingredient Clodronate 100 mg/3.3 ml injectable solution - 6 ampoules 100 mg/3.3 ml injectable solution - 12 ampoules 300 mg/10 ml solution for infusion I.V. Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. inibe a reabsorção óssea que leva a aumento do cálcio no sangue. - 6 ampoules You may have sodium clodronate for 1 of the following reasons: to treat high blood calcium (hypercalcaemia) Parecoxib. EY = Eye. Manufacturer advises avoid. Special pediatric considerations are noted when applicable, otherwise adult provisions apply. Brand Name: Clophosome ® Active: clodronate disodium. Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. Brands / Trade Names of Clodronate. Adverse reactions include renal insufficiency and hypocalcaemia. Patients must be adequately hydrated before treatment and renal function must be monitored. Sodium clodronate (as tetrahydrate). Perspectives from an Equine Expert Panel on Clodronate Use in Horses. 1600 mg por dia, em dose única. THE GOOD NEWS is that there is finally an effective treatment for bone cancer—a drug named clodronate. It is used to treat hypercalcemia (high blood calcium) for people who have cancer. By mouth. Cancer. Do not take sodium clodronate at the same time as food or other medications because they may prevent its absorption. Clodronate is not metabolised and most of the dose appears in the urine within a few days. Brand names and generic names are differentiated by the use of capital initials for the former.. See also the list of the top 100 bestselling branded drugs, ranked by sales. Suggested Pages. refrigeração (2-8°C): 24 horas. •pode ter sua ação diminuída por: alimento com alto teor de cálcio (leite e laticínios); antiácido; droga contendo ferro, cálcio ou magnésio. Disclaimer. •com 1 copo cheio de água, em jejum, pelo menos 30 minutos antes do café da manhã. Clodronate is also used to treat cancer that has spread to bones (bone metastases) due to different types of tumours. Em função da pandemia do Coronavírus informamos que não estaremos prestando atendimento telefônico temporariamente. BV = Blood vessels (circulation) BR = Brain. You might have it as a treatment for a number of cancers that affect the bones such as myeloma and secondary breast cancer. Popular Products. Company: Berlex, Inc. Weight: 02 kg: Quantity: 5 ml (5ml Clodronate Liposomes), 10 ml (10ml Clodronate Liposomes), 15 ml (15ml Clodronate Liposomes), 20ml (20ml Clodronate Liposomes), 25 ml (25ml Clodronate Liposomes), 30 ml (30ml Clodronate Liposomes), 40 ml (40ml Clodronate Liposomes), 50 ml (50ml Clodronate Liposomes), 60 ml (60ml Clodronate Liposomes), 70 ml (70ml Clodronate Liposomes), 80 ml (80ml Clodronate … Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. inibidor da reabsorção óssea [pirofosfato (derivado); ácido clodrônico (sal do); bifosfonato]. It is also used to treat a high level of calcium in the blood that may occur with some cancers. Kanis JA(1), McCloskey EV. Cited in 1 publications Reações mais comuns (sem incidência definida): Fechamento de Forame Oval Patente ou Anticoagulação em Comparação Com Antiplaquetários Após AVC, Diretriz da SBC Para Gravidez na Mulher Cardiopata (parte 5/17), Risco de Suicídio e Morte Cardiovascular Após o Diagnóstico de Câncer, 6 Medicamentos Utilizados no Manejo Das Neoplasias, Infecção Latente Por M. Tuberculosis e Atualização Terapêutica - Dr. Marcelo Litvoc - 50 Min - 09/1, Estratégia Transfusional Liberal ou Restritiva Após Cirurgia de Quadril em Pacientes de Alto Risco, Suporte Avançado - Dr. Ricardo Casalino Sanches de Moraes - 52 Min - 11/10, 3.4 Medicamentos Utilizados no Tratamento da Gota, Manual de Implementação do Checklist: Parte II - Antes de Iniciar a Cirurgia. Clodronato dissódico (solução) 1500 mg/25 mL – Infusão intravenosa. Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. Each standard macrophage depletion kit contains one vial of Clodronate encapsulated liposomes (Clodrosome) and one vial of plain liposome for control (Encapsome) with the same lipid composition as Clodrosome. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Diluente: Cloreto de Sódio 0,9% ou Glicose 5%. Author information: (1)World Health Organization Collaborating Centre for Metabolic Bone Diseases, Department of Human Metabolism and Clinical Biochemistry, University of Sheffield Medical School, United Kingdom. DA = Draining area of lymph node. Clodronate has been extensively used in patients with advanced breast cancer, and is generally well tolerated. Brand name: Bonefos. Clodronate is predicted to decrease the effects of parathyroid hormone. inflamação aguda do estômago ou intestino; diminuição da função renal. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Read More. Você está em: Inicial © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Clodronato dissódico tetraidratado equivalente a clodronato dissódico. Macrophage Depletion Kit (Mannosylated) Take this medication 1 to 2 hours (depending on your brand) before or 1 to 2 hours after taking any products that contain aluminum, calcium, iron, magnesium, or zinc. Clodronate. A dose máxima diária é de 3200 mg. A duração do tratamento é, em geral, de 6 meses. Lipid composition: phosphatidylcholine and cholesterol. MF: CH2Cl2O6P2Na2, MW: 288.86. geniturinário: eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. Treatment for: Breast Cancer, Adjuvant. •realizar periodicamente exames de sangue e da função do fígado. Clodronate Synthesis Reference No information avaliable Developer and worldwide provider of clodronate liposomes: Delivery on demand + Worldwide shipping & Easy Online Ordering 24/7 - Please Contact Us All rights reserved. Injetável (solução) 1500 mg/25 mL: Bonefós Injetável (solução) 300 mg/5 mL: Bonefós O que é Brand Names: Canada. All rights reserved. Permanecemos com suporte aos nossos inscritos através do e-mail info@medicinanet.com.br. classificação não disponibilizada; não usar. Bonefos [DSC]; Clasteon. 1997 Oct 15;80(8 Suppl):1691-5. Clodronate molecules are encapsulated in small MLV liposomes for superior activity, physical and chemical stability, and convenience of use and handling. Hematológico: diminuição do cálcio no sangue. The bad news is that clodronate is not directly available in the United States. •evitar deitar por pelo menos 30 minutos. Name of the medicine. It is used to treat high calcium levels in patients with cancer. Diluente: Cloreto de Sódio 0,9%. What do I need to tell my doctor BEFORE I take this drug? Clodronate belongs to a family of medications known as bisphosphonates. The terminal elimination half-life may exceed a year as clodronate bound to bone is slowly released. Back to top. Clodronate Brand Names Mixture No information avaliable; Clodronate Chemical_Formula CH 4 Cl 2 O 6 P 2. Clodronate. Clodronic acid is approved for human use in Canada and Australia, the United Kingdom, where it is marketed as Bonefos, Loron, Clodron and in Italy as Clasteon, Difosfonal, Osteostab and several generics. Bonefos Bayer, United Kingdom; Bayer, Tunisia; Er-Kim, Turkey; IFET, Greece Background. Mayo Clinic does not endorse companies or products. All products: If you have an allergy to clodronate … In other countries is prescribed as a bone resorption inhibitor and antihypercalcemic agent. 1.6 g daily in 1–2 divided doses, then increased if necessary up to 3.2 g daily in 2 divided doses. Volume: 500 mL. CAS: 22560-50-5, 7 mg/mL . Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Clodronic Acid (Oral Route, Injection Route), FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Cápsula 400 mg: Bonefós Uso injetável. Clodronato (Oral; Injetável) (substância ativa) Referência: Bonefós (Bayer). Back to top. This site complies with the HONcode standard for trustworthy health information: verify here. It is used to stop bone loss. Volume: 500 mL. Genérico: não clodronato dissódico tetraidratado equivalente a clodronato dissódico Uso oral. Clodronato dissódico (solução) 300 mg/5 mL – Infusão intravenosa. Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. Manufacturers of Clodronate in Pakistan. Clodronate, Disodium Salt, CAS: 22560-50-5, is A bisphosphonate apoptosis inducing agent. Clodronate. Bonefos (clodronate) is a non-amino bisphosphonate intended to reduce the occurrence of bone metastases in the post-surgical (adjuvant) treatment of breast cancer patients. GU = Gut (intestines) •doses em termos de Clodronato dissódico. Each capsule contains the equivalent of … It is also called Bonefos, Clasteon, and Loron 520 Copyright © 2021 IBM Watson Health. Portions of this document last updated: Feb. 01, 2020. Few diseases are as dehumanizing and as damaging to a … Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): 6 horas. temperatura ambiente (15 - 25°C): 24 horas. For SODIUM CLODRONATE. : eliminação de proteínas pela urina ; insuficiência renal aguda após administração intravenosa portions this! Advanced breast cancer perspectives from an Equine Expert Panel on clodronate use in Horses água, em,... ), pH 7.0-7.5 Popular products Privacy Policy linked below available only your! Bonefós ( Bayer ) from another part of the body tratamento se comprometimento... Cancer or multiple myeloma the bones from another part of the body ambiente ( 15 - 25°C:. User 's use only and may not be sold, redistributed or otherwise used for commercial.... Warnings and other safety information for sodium clodronate is predicted to decrease the effects of parathyroid hormone an allergy clodronate! 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Is used to treat high calcium levels in patients with advanced breast cancer sheet clodronate msds material! Any use of this site constitutes your agreement to the bones from another part of the body skeletal metastases patients! An effective treatment for bone cancer—a drug named clodronate genérico: não clodronato dissódico ( solução 1500... Dose máxima diária é de 3200 mg. a duração do tratamento é, em jejum, pelo menos minutos! Is for End User 's use only and may not be sold, redistributed or used. ) is a capsule that you take by mouth bone caused by cancer that has spread to bones! Different types of tumours effective treatment for bone cancer—a drug named clodronate e-newsletter keeps you up to date on wide!

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